Tag: TMP-SMX warfarin interaction

Trimethoprim-Sulfamethoxazole and Warfarin: What You Need to Know About INR Elevation

Trimethoprim-sulfamethoxazole (Bactrim) can dangerously raise INR in patients on warfarin, increasing bleeding risk. Learn why this interaction happens, who's most at risk, and how to prevent life-threatening complications.