Prednisone Price Guide – What You’ll Pay in 2025 and How to Save

If you’ve been prescribed prednisone, the first thing on your mind is probably the price tag. The good news? It’s not always as pricey as you think, but a lot depends on where you shop, your dosage, and whether you have insurance.

What Does Prednisone Usually Cost?

In the United States, a typical 10‑mg tablet of generic prednisone costs between $0.20 and $1 per pill when you pay out‑of‑pocket. That means a 30‑day supply can range from $6 to $30. Brand‑name versions like Deltasone are more expensive – often $2‑$3 per tablet, pushing the monthly bill over $100.

Factors That Change the Price

Dosage matters a lot. Higher strengths (20 mg or 40 mg) cost more per pill and you’ll need fewer tablets, but the total price still climbs. Insurance coverage can cut the cost dramatically; many plans cover generic prednisone with little to no copay.

Pharmacy type is another big factor. Big‑box chains usually have lower list prices than small independent stores. Online pharmacies that are US‑licensed often offer the best deals, especially if you use a discount card or pay with cash.

If you’re buying for chronic conditions, ask your doctor about 90‑day supplies. Most insurers and many online pharmacies give a bulk discount that can shave $5‑$15 off a month’s cost.

Don’t forget coupons. Websites like GoodRx, Blink Health, or the pharmacy’s own savings program often list a coupon code you can paste at checkout for an instant discount.

When you compare prices, look at the “price per tablet” rather than the total bill. A $30 bottle of 100 mg tablets might seem cheap, but if you only need 10 mg, you’re overpaying.

Safety first: Only order from pharmacies that require a prescription and display a verified US address. Check for a “Verified Internet Pharmacy Practice Sites” (VIPPS) seal or the NABP logo.

Here’s a quick checklist to lock in the best price:

• Ask your doctor if a generic version works for you.
• Check GoodRx or Blink Health for coupons before heading to the counter.
• Compare at least three pharmacies – local, chain, and online.
• Consider a 90‑day supply if it’s a long‑term prescription.
• Make sure the pharmacy is US‑licensed and requires a prescription.

Bottom line: Prednisone doesn’t have to break the bank. By knowing where prices differ, using coupons, and choosing reputable online options, you can keep your monthly cost well under $20 for most people.